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The role of charged surface residues in the binding ability of small hubs in protein-protein interaction networks

Hubs are highly connected proteins in a protein-protein interaction network. Previous work has implicated disordered domains and high surface charge as the properties significant in the ability of hubs to bind multiple proteins. While conformational flexibility of disordered domains plays an importa...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Biophysics (Nagoya-shi)
Main Authors: Patil, Ashwini, Nakamura, Haruki
Format: Artigo
Jezik:Inglês
Izdano: The Biophysical Society of Japan (BSJ) 2007
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5036656/
https://ncbi.nlm.nih.gov/pubmed/27857564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2142/biophysics.3.27
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