From the Cover: Arsenic Induces Accumulation of α-Synuclein: Implications for Synucleinopathies and Neurodegeneration

Synucleinopathies, including Parkinson’s disease (PD), are neurodegenerative diseases characterized by accumulation of α-synuclein (SYN), a small neuronal protein with prion like properties that plays a central role in PD pathogenesis. SYN can misfold and generate toxic oligomers/aggregates, which c...

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Udgivet i:Toxicol Sci
Main Authors: Cholanians, Aram B., Phan, Andy V., Ditzel, Eric J., Camenisch, Todd D., Lau, Serrine S., Monks, Terrence J.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2016
Fag:
Arsenic, α-Synuclein, and Neurodegeneration
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5036614/
https://ncbi.nlm.nih.gov/pubmed/27413109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfw117
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