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Meta-analysis of Genome Wide Association Studies Identifies Genetic Markers of Late Toxicity Following Radiotherapy for Prostate Cancer

Nearly 50% of cancer patients undergo radiotherapy. Late radiotherapy toxicity affects quality-of-life in long-term cancer survivors and risk of side-effects in a minority limits doses prescribed to the majority of patients. Development of a test predicting risk of toxicity could benefit many cancer...

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Vydáno v:EBioMedicine
Hlavní autoři: Kerns, Sarah L., Dorling, Leila, Fachal, Laura, Bentzen, Søren, Pharoah, Paul D.P., Barnes, Daniel R., Gómez-Caamaño, Antonio, Carballo, Ana M., Dearnaley, David P., Peleteiro, Paula, Gulliford, Sarah L., Hall, Emma, Michailidou, Kyriaki, Carracedo, Ángel, Sia, Michael, Stock, Richard, Stone, Nelson N., Sydes, Matthew R., Tyrer, Jonathan P., Ahmed, Shahana, Parliament, Matthew, Ostrer, Harry, Rosenstein, Barry S., Vega, Ana, Burnet, Neil G., Dunning, Alison M., Barnett, Gillian C., West, Catharine M.L.
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5036513/
https://ncbi.nlm.nih.gov/pubmed/27515689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2016.07.022
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