A naturally occurring bovine APOBEC3 confers resistance to bovine lentiviruses: implication for the co-evolution of bovids and their lentiviruses

Mammals have co-evolved with lentiviruses for a long time. As evidence, viral infectivity factor (Vif), encoded by lentiviruses, antagonizes the anti-viral action of cellular APOBEC3 of their hosts. Here, we address the co-evolutionary dynamics of bovine APOBEC3 and the following two bovine lentivir...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Yamada, Eri, Yoshikawa, Rokusuke, Nakano, Yusuke, Misawa, Naoko, Kobayashi, Tomoko, Ren, Fengrong, Izumi, Taisuke, Miyazawa, Takayuki, Koyanagi, Yoshio, Sato, Kei
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5036201/
https://ncbi.nlm.nih.gov/pubmed/27665724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep33988
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