Palmitoyl acyltransferase DHHC21 mediates endothelial dysfunction in systemic inflammatory response syndrome

Endothelial dysfunction is a hallmark of systemic inflammatory response underlying multiple organ failure. Here we report a novel function of DHHC-containing palmitoyl acyltransferases (PATs) in mediating endothelial inflammation. Pharmacological inhibition of PATs attenuates barrier leakage and leu...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Beard, Richard S., Yang, Xiaoyuan, Meegan, Jamie E., Overstreet, Jonathan W., Yang, Clement G.Y., Elliott, John A., Reynolds, Jason J., Cha, Byeong J., Pivetti, Christopher D., Mitchell, David A., Wu, Mack H., Deschenes, Robert J., Yuan, Sarah Y.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5036164/
https://ncbi.nlm.nih.gov/pubmed/27653213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms12823
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados