Topoisomerase IIα mediates TCF-dependent epithelial–mesenchymal transition in colon cancer

Aberrant T-cell factor (TCF) transcription is implicated in the majority of colorectal cancers (CRCs). TCF transcription induces epithelial–mesenchymal transition (EMT), promoting a tumor-initiating cell (TIC) phenotype characterized by increased proliferation, multidrug resistance (MDR), invasion a...

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Detalhes bibliográficos
Publicado no:Oncogene
Main Authors: Zhou, Q, Abraham, A D, Li, L, Babalmorad, A, Bagby, S, Arcaroli, J J, Hansen, R J, Valeriote, F A, Gustafson, D L, Schaack, J, Messersmith, W A, LaBarbera, D V
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5036162/
https://ncbi.nlm.nih.gov/pubmed/26947016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2016.29
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