Dephosphorylated parafibromin is a transcriptional coactivator of the Wnt/Hedgehog/Notch pathways

Evolutionally conserved Wnt, Hedgehog (Hh) and Notch morphogen pathways play essential roles in the development, homeostasis and pathogenesis of multicellular organisms. Nevertheless, mechanisms that intracellularly coordinate these signal inputs remain poorly understood. Here we found that parafibr...

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Publicat a:Nat Commun
Autors principals: Kikuchi, Ippei, Takahashi-Kanemitsu, Atsushi, Sakiyama, Natsuki, Tang, Chao, Tang, Pei-Jung, Noda, Saori, Nakao, Kazuki, Kassai, Hidetoshi, Sato, Toshiro, Aiba, Atsu, Hatakeyama, Masanori
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2016
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5036006/
https://ncbi.nlm.nih.gov/pubmed/27650679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms12887
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