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Dephosphorylated parafibromin is a transcriptional coactivator of the Wnt/Hedgehog/Notch pathways

Evolutionally conserved Wnt, Hedgehog (Hh) and Notch morphogen pathways play essential roles in the development, homeostasis and pathogenesis of multicellular organisms. Nevertheless, mechanisms that intracellularly coordinate these signal inputs remain poorly understood. Here we found that parafibr...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Kikuchi, Ippei, Takahashi-Kanemitsu, Atsushi, Sakiyama, Natsuki, Tang, Chao, Tang, Pei-Jung, Noda, Saori, Nakao, Kazuki, Kassai, Hidetoshi, Sato, Toshiro, Aiba, Atsu, Hatakeyama, Masanori
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5036006/
https://ncbi.nlm.nih.gov/pubmed/27650679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms12887
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