Selenoprotein H is an essential regulator of redox homeostasis that cooperates with p53 in development and tumorigenesis

Selenium, an essential micronutrient known for its cancer prevention properties, is incorporated into a class of selenocysteine-containing proteins (selenoproteins). Selenoprotein H (SepH) is a recently identified nucleolar oxidoreductase whose function is not well understood. Here we report that se...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Cox, Andrew G., Tsomides, Allison, Kim, Andrew J., Saunders, Diane, Hwang, Katie L., Evason, Kimberley J., Heidel, Jerry, Brown, Kristin K., Yuan, Min, Lien, Evan C., Lee, Byung Cheon, Nissim, Sahar, Dickinson, Bryan, Chhangawala, Sagar, Chang, Christopher J., Asara, John M., Houvras, Yariv, Gladyshev, Vadim N., Goessling, Wolfram
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2016
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PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5035897/
https://ncbi.nlm.nih.gov/pubmed/27588899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1600204113
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