Minibrain and Wings apart control organ growth and tissue patterning through down-regulation of Capicua

The transcriptional repressor Capicua (Cic) controls tissue patterning and restricts organ growth, and has been recently implicated in several cancers. Cic has emerged as a primary sensor of signaling downstream of the receptor tyrosine kinase (RTK)/extracellular signal-regulated kinase (ERK) pathwa...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Yang, Liu, Paul, Sayantanee, Trieu, Kenneth G., Dent, Lucas G., Froldi, Francesca, Forés, Marta, Webster, Kaitlyn, Siegfried, Kellee R., Kondo, Shu, Harvey, Kieran, Cheng, Louise, Jiménez, Gerardo, Shvartsman, Stanislav Y., Veraksa, Alexey
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2016
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5035877/
https://ncbi.nlm.nih.gov/pubmed/27601662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1609417113
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