Coordinated autoinhibition of F-BAR domain membrane binding and WASp activation by Nervous Wreck

Membrane remodeling by Fes/Cip4 homology-Bin/Amphiphysin/Rvs167 (F-BAR) proteins is regulated by autoinhibitory interactions between their SRC homology 3 (SH3) and F-BAR domains. The structural basis of autoregulation, and whether it affects interactions of SH3 domains with other cellular ligands, r...

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Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Stanishneva-Konovalova, Tatiana B., Kelley, Charlotte F., Eskin, Tania L., Messelaar, Emily M., Wasserman, Steven A., Sokolova, Olga S., Rodal, Avital A.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2016
Fag:
PNAS Plus
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5035868/
https://ncbi.nlm.nih.gov/pubmed/27601635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1524412113
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