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Infiltrating monocytes promote brain inflammation and exacerbate neuronal damage after status epilepticus

The generalized seizures of status epilepticus (SE) trigger a series of molecular and cellular events that produce cognitive deficits and can culminate in the development of epilepsy. Known early events include opening of the blood–brain barrier (BBB) and astrocytosis accompanied by activation of br...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Varvel, Nicholas H., Neher, Jonas J., Bosch, Andrea, Wang, Wenyi, Ransohoff, Richard M., Miller, Richard J., Dingledine, Raymond
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5035862/
https://ncbi.nlm.nih.gov/pubmed/27601660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1604263113
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