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Metabolomics Beyond Spectroscopic Databases: A Combined MS/NMR Strategy for the Rapid Identification of New Metabolites in Complex Mixtures

A novel strategy is introduced that combines high-resolution mass spectrometry (MS) with NMR for the identification of unknown components in complex metabolite mixtures encountered in metabolomics. The approach first identifies the chemical formulas of the mixture components from accurate masses by...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Anal Chem
Hauptverfasser: Bingol, Kerem, Bruschweiler-Li, Lei, Yu, Cao, Somogyi, Arpad, Zhang, Fengli, Brüschweiler, Rafael
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5035699/
https://ncbi.nlm.nih.gov/pubmed/25674812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac504633z
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