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Metabolomics Beyond Spectroscopic Databases: A Combined MS/NMR Strategy for the Rapid Identification of New Metabolites in Complex Mixtures

A novel strategy is introduced that combines high-resolution mass spectrometry (MS) with NMR for the identification of unknown components in complex metabolite mixtures encountered in metabolomics. The approach first identifies the chemical formulas of the mixture components from accurate masses by...

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Detalhes bibliográficos
Publicado no:Anal Chem
Main Authors: Bingol, Kerem, Bruschweiler-Li, Lei, Yu, Cao, Somogyi, Arpad, Zhang, Fengli, Brüschweiler, Rafael
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5035699/
https://ncbi.nlm.nih.gov/pubmed/25674812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac504633z
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