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Role of Aryl Hydrocarbon Receptor Polymorphisms on TCDD-mediated CYP1B1 Induction and IgM Suppression by Human B cells

Previous studies have demonstrated that most of the intraspecies variation in sensitivity to the toxic effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), including suppression of antibody responses, in murine models is due to single nucleotide polymorphisms (SNPs) within the aryl hydrocarbon rec...

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Detalhes bibliográficos
Publicado no:Toxicol Appl Pharmacol
Main Authors: Kovalova, Natalia, Manzan, Maria, Crawford, Robert, Kaminski, Norbert
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5035641/
https://ncbi.nlm.nih.gov/pubmed/27535091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2016.08.011
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