Aryl hydrocarbon receptor-dependent upregulation of Cyp1b1 by TCDD and diesel exhaust particles in rat brain microvessels

BACKGROUND: AhR activates the transcription of several target genes including CYP1B1. Recently, we showed CYP1B1 as the major cytochrome P450 (CYP) enzyme expressed in human brain microvessels. Here, we studied the effect of AhR activation by environmental pollutants on the expression of Cyp1b1 in r...

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Detalhes bibliográficos
Main Authors: Jacob, Aude, Hartz, Anika MS, Potin, Sophie, Coumoul, Xavier, Yousif, Salah, Scherrmann, Jean-Michel, Bauer, Björn, Declèves, Xavier
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3180256/
https://ncbi.nlm.nih.gov/pubmed/21867498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2045-8118-8-23
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