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Lentiviral Vector-Mediated Correction of a Mouse Model of Leukocyte Adhesion Deficiency Type I
Leukocyte adhesion deficiency type I (LAD-I) is a primary immunodeficiency caused by mutations in the ITGB2 gene and is characterized by recurrent and life-threatening bacterial infections. These mutations lead to defective or absent expression of β(2) integrins on the leukocyte surface, compromisin...
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| Publicat a: | Hum Gene Ther |
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| Autors principals: | , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Mary Ann Liebert, Inc.
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5035374/ https://ncbi.nlm.nih.gov/pubmed/27056660 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2016.016 |
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