PCM1 Depletion Inhibits Glioblastoma Cell Ciliogenesis and Increases Cell Death and Sensitivity to Temozolomide()

A better understanding of the molecules implicated in the growth and survival of glioblastoma (GBM) cells and their response to temozolomide (TMZ), the standard-of-care chemotherapeutic agent, is necessary for the development of new therapies that would improve the outcome of current GBM treatments....

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Publicat a:Transl Oncol
Autors principals: Hoang-Minh, Lan B., Deleyrolle, Loic P., Nakamura, Nariaki S., Parker, Alexander K., Martuscello, Regina T., Reynolds, Brent A., Sarkisian, Matthew R.
Format: Artigo
Idioma:Inglês
Publicat: Neoplasia Press 2016
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Original article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5035360/
https://ncbi.nlm.nih.gov/pubmed/27661404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tranon.2016.08.006
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