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Critical Role of IRF-3 in the Direct Regulation of dsRNA-Induced Retinoic Acid-Inducible Gene-I (RIG-I) Expression

The cytoplasmic viral sensor retinoic acid-inducible gene-I (RIG-I), which is also known as an IFN-stimulated gene (ISG), senses viral RNA to activate antiviral signaling. It is therefore thought that RIG-I is regulated in a STAT1-dependent manner. Although RIG-I-mediated antiviral signaling is indi...

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Bibliografski detalji
Izdano u:PLoS One
Glavni autori: Hayakari, Ryo, Matsumiya, Tomoh, Xing, Fei, Yoshida, Hidemi, Hayakari, Makoto, Imaizumi, Tadaatsu
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5035021/
https://ncbi.nlm.nih.gov/pubmed/27662626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0163520
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