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A Novel Hydrogen Sulfide Prodrug, SG1002, Promotes Hydrogen Sulfide and Nitric Oxide Bioavailability in Heart Failure Patients

Recent studies demonstrate robust molecular cross talk and signaling between hydrogen sulfide (H(2)S) and nitric oxide (NO). Heart failure (HF) patients are deficient in both H(2)S and NO, two molecules that are critical for cardiovascular homeostasis. A phase I clinical trial of a novel H(2)S prodr...

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Detalhes bibliográficos
Publicado no:Cardiovasc Ther
Main Authors: Polhemus, David J., Li, Zhen, Pattillo, Christopher B., Gojon, Gabriel, Giordano, Tony, Krum, Henry
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5034803/
https://ncbi.nlm.nih.gov/pubmed/25930144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/1755-5922.12128
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