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A Novel Hydrogen Sulfide Prodrug, SG1002, Promotes Hydrogen Sulfide and Nitric Oxide Bioavailability in Heart Failure Patients

Recent studies demonstrate robust molecular cross talk and signaling between hydrogen sulfide (H(2)S) and nitric oxide (NO). Heart failure (HF) patients are deficient in both H(2)S and NO, two molecules that are critical for cardiovascular homeostasis. A phase I clinical trial of a novel H(2)S prodr...

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Vydáno v:Cardiovasc Ther
Hlavní autoři: Polhemus, David J., Li, Zhen, Pattillo, Christopher B., Gojon, Gabriel, Giordano, Tony, Krum, Henry
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5034803/
https://ncbi.nlm.nih.gov/pubmed/25930144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/1755-5922.12128
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