Silencing of GATA3 defines a novel stem cell-like subgroup of ETP-ALL

BACKGROUND: GATA3 is pivotal for the development of T lymphocytes. While its effects in later stages of T cell differentiation are well recognized, the role of GATA3 in the generation of early T cell precursors (ETP) has only recently been explored. As aberrant GATA3 mRNA expression has been linked...

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Publicado en:J Hematol Oncol
Autores principales: Fransecky, L., Neumann, M., Heesch, S., Schlee, C., Ortiz-Tanchez, J., Heller, S., Mossner, M., Schwartz, S., Mochmann, L. H., Isaakidis, K., Bastian, L., Kees, U. R., Herold, T., Spiekermann, K., Gökbuget, N., Baldus, C. D.
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5034449/
https://ncbi.nlm.nih.gov/pubmed/27658391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-016-0324-8
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