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Blocking 5-HT2 receptor restores cardiovascular disorders in type 1 experimental diabetes

This study aimed to determine whether the serotonergic modulation, through selective 5-HT(2) receptor blockade, restores cardiovascular disturbances in type 1 diabetic rats. Diabetes was induced by alloxan (150 mg/kg, s.c.) and maintained for 4 weeks. 5-HT(2) receptor was blocked by sarpogrelate (30...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Sci Rep
Prif Awduron: García-Pedraza, José-Ángel, Ferreira-Santos, Pedro, Aparicio, Rubén, Montero, María-José, Morán, Asunción
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2016
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5034292/
https://ncbi.nlm.nih.gov/pubmed/27659784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep33979
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