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Prevention of allograft rejection in heart transplantation through concurrent gene silencing of TLR and Kinase signaling pathways
Toll-like receptors (TLRs) act as initiators and conductors responsible for both innate and adaptive immune responses in organ transplantation. The mammalian target of rapamycin (mTOR) is one of the most critical signaling kinases that affects broad aspects of cellular functions including metabolism...
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| Publicado no: | Sci Rep |
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| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5034230/ https://ncbi.nlm.nih.gov/pubmed/27659428 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep33869 |
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