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Prevention of allograft rejection in heart transplantation through concurrent gene silencing of TLR and Kinase signaling pathways
Toll-like receptors (TLRs) act as initiators and conductors responsible for both innate and adaptive immune responses in organ transplantation. The mammalian target of rapamycin (mTOR) is one of the most critical signaling kinases that affects broad aspects of cellular functions including metabolism...
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| 出版年: | Sci Rep |
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| 主要な著者: | , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group
2016
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5034230/ https://ncbi.nlm.nih.gov/pubmed/27659428 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep33869 |
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