Prevention of allograft rejection in heart transplantation through concurrent gene silencing of TLR and Kinase signaling pathways

Toll-like receptors (TLRs) act as initiators and conductors responsible for both innate and adaptive immune responses in organ transplantation. The mammalian target of rapamycin (mTOR) is one of the most critical signaling kinases that affects broad aspects of cellular functions including metabolism...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Wang, Hongmei, Zhang, Xusheng, Zheng, Xiufen, Lan, Zhu, Shi, Jun, Jiang, Jifu, Zwiep, Terry, Li, Qing, Quan, Douglas, Zhang, Zhu-Xu, Min, Weiping
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5034230/
https://ncbi.nlm.nih.gov/pubmed/27659428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep33869
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