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The Central domain of RyR1 is the transducer for long-range allosteric gating of channel opening
The ryanodine receptors (RyRs) are intracellular calcium channels responsible for rapid release of Ca(2+) from the sarcoplasmic/endoplasmic reticulum (SR/ER) to the cytoplasm, which is essential for the excitation-contraction (E-C) coupling of cardiac and skeletal muscles. The near-atomic resolution...
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| Udgivet i: | Cell Res |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5034110/ https://ncbi.nlm.nih.gov/pubmed/27468892 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2016.89 |
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