Eicosapentaenoic Acid Potentiates Brown Thermogenesis through FFAR4-dependent Up-regulation of miR-30b and miR-378

Emerging evidence suggests that n-3 polyunsaturated fatty acids (PUFA) promote brown adipose tissue thermogenesis. However, the underlying mechanisms remain elusive. Here, we hypothesize that n-3 PUFA promotes brown adipogenesis by modulating miRNAs. To test this hypothesis, murine brown preadipocyt...

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Vydáno v:J Biol Chem
Hlavní autoři: Kim, Jiyoung, Okla, Meshail, Erickson, Anjeza, Carr, Timothy, Natarajan, Sathish Kumar, Chung, Soonkyu
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2016
Témata:
Metabolism
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5034049/
https://ncbi.nlm.nih.gov/pubmed/27489163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.721480
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