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Eicosapentaenoic Acid Potentiates Brown Thermogenesis through FFAR4-dependent Up-regulation of miR-30b and miR-378

Emerging evidence suggests that n-3 polyunsaturated fatty acids (PUFA) promote brown adipose tissue thermogenesis. However, the underlying mechanisms remain elusive. Here, we hypothesize that n-3 PUFA promotes brown adipogenesis by modulating miRNAs. To test this hypothesis, murine brown preadipocyt...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Kim, Jiyoung, Okla, Meshail, Erickson, Anjeza, Carr, Timothy, Natarajan, Sathish Kumar, Chung, Soonkyu
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5034049/
https://ncbi.nlm.nih.gov/pubmed/27489163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.721480
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