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Retinal Hypercholesterolemia Triggers Cholesterol Accumulation and Esterification in Photoreceptor Cells

The process of vision is impossible without the photoreceptor cells, which have a unique structure and specific maintenance of cholesterol. Herein we report on the previously unrecognized cholesterol-related pathway in the retina discovered during follow-up characterizations of Cyp27a1(−/−)Cyp46a1(−...

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Détails bibliographiques
Publié dans:J Biol Chem
Auteurs principaux: Saadane, Aicha, Mast, Natalia, Dao, Tung, Ahmad, Baseer, Pikuleva, Irina A.
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5034040/
https://ncbi.nlm.nih.gov/pubmed/27514747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.744656
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