Identification of microRNA-181a-5p and microRNA-4454 as mediators of facet cartilage degeneration

Osteoarthritis (OA) of spine (facet joints [FJs]) is one of the major causes of severe low back pain and disability worldwide. The degeneration of facet cartilage is a hallmark of FJ OA. However, endogenous mechanisms that initiate degeneration of facet cartilage are unknown, and there are no diseas...

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Veröffentlicht in:JCI Insight
Hauptverfasser: Nakamura, Akihiro, Rampersaud, Y. Raja, Sharma, Anirudh, Lewis, Stephen J., Wu, Brian, Datta, Poulami, Sundararajan, Kala, Endisha, Helal, Rossomacha, Evgeny, Rockel, Jason S., Jurisica, Igor, Kapoor, Mohit
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2016
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5033882/
https://ncbi.nlm.nih.gov/pubmed/27699225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.86820
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