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Increased apoptosis and browning of TAK1-deficient adipocytes protects against obesity
Obesity is an increasing health problem worldwide, and nonsurgical strategies to treat obesity have remained rather inefficient. We here show that acute loss of TGF-β–activated kinase 1 (TAK1) in adipocytes results in an increased rate of apoptotic adipocyte death and increased numbers of M2 macroph...
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| 發表在: | JCI Insight |
|---|---|
| Main Authors: | , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Society for Clinical Investigation
2016
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5033847/ https://ncbi.nlm.nih.gov/pubmed/27699262 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.81175 |
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