A cord blood monocyte–derived cell therapy product accelerates brain remyelination

Microglia and monocytes play important roles in regulating brain remyelination. We developed DUOC-01, a cell therapy product intended for treatment of demyelinating diseases, from banked human umbilical cord blood (CB) mononuclear cells. Immunodepletion and selection studies demonstrated that DUOC-0...

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Vydáno v:JCI Insight
Hlavní autoři: Saha, Arjun, Buntz, Susan, Scotland, Paula, Xu, Li, Noeldner, Pamela, Patel, Sachit, Wollish, Amy, Gunaratne, Aruni, Gentry, Tracy, Troy, Jesse, Matsushima, Glenn K., Kurtzberg, Joanne, Balber, Andrew E.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2016
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5033827/
https://ncbi.nlm.nih.gov/pubmed/27699230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.86667
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