Human umbilical cord blood monocytes, but not adult blood monocytes, rescue brain cells from hypoxic-ischemic injury: Mechanistic and therapeutic implications

Cord blood (CB) mononuclear cells (MNC) are being tested in clinical trials to treat hypoxic-ischemic (HI) brain injuries. Although early results are encouraging, mechanisms underlying potential clinical benefits are not well understood. To explore these mechanisms further, we exposed mouse brain or...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:PLoS One
Egile Nagusiak: Saha, Arjun, Patel, Sachit, Xu, Li, Scotland, Paula, Schwartzman, Jonathan, Filiano, Anthony J., Kurtzberg, Joanne, Balber, Andrew E.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2019
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6726370/
https://ncbi.nlm.nih.gov/pubmed/31483780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0218906
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