Safety and efficacy of the JAK inhibitor tofacitinib citrate in patients with alopecia areata

BACKGROUND. Alopecia areata (AA) is an autoimmune disease characterized by hair loss mediated by CD8(+) T cells. There are no reliably effective therapies for AA. Based on recent developments in the understanding of the pathomechanism of AA, JAK inhibitors appear to be a therapeutic option; however,...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Kennedy Crispin, Milène, Ko, Justin M., Craiglow, Brittany G., Li, Shufeng, Shankar, Gautam, Urban, Jennifer R., Chen, James C., Cerise, Jane E., Jabbari, Ali, Winge, Mårten C.G., Marinkovich, M. Peter, Christiano, Angela M., Oro, Anthony E., King, Brett A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2016
Assuntos:
Clinical Medicine
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5033755/
https://ncbi.nlm.nih.gov/pubmed/27699252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.89776
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