Safety and efficacy of the JAK inhibitor tofacitinib citrate in patients with alopecia areata

BACKGROUND. Alopecia areata (AA) is an autoimmune disease characterized by hair loss mediated by CD8(+) T cells. There are no reliably effective therapies for AA. Based on recent developments in the understanding of the pathomechanism of AA, JAK inhibitors appear to be a therapeutic option; however,...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:JCI Insight
Prif Awduron: Kennedy Crispin, Milène, Ko, Justin M., Craiglow, Brittany G., Li, Shufeng, Shankar, Gautam, Urban, Jennifer R., Chen, James C., Cerise, Jane E., Jabbari, Ali, Winge, Mårten C.G., Marinkovich, M. Peter, Christiano, Angela M., Oro, Anthony E., King, Brett A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Clinical Investigation 2016
Pynciau:
Clinical Medicine
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5033755/
https://ncbi.nlm.nih.gov/pubmed/27699252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.89776
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