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An MSC2 Promoter-lacZ Fusion Gene Reveals Zinc-Responsive Changes in Sites of Transcription Initiation That Occur across the Yeast Genome

The Msc2 and Zrg17 proteins of Saccharomyces cerevisiae form a complex to transport zinc into the endoplasmic reticulum. ZRG17 is transcriptionally induced in zinc-limited cells by the Zap1 transcription factor. In this report, we show that MSC2 mRNA also increases (~1.5 fold) in zinc-limited cells....

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Wu, Yi-Hsuan, Taggart, Janet, Song, Pamela Xiyao, MacDiarmid, Colin, Eide, David J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5033525/
https://ncbi.nlm.nih.gov/pubmed/27657924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0163256
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