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Peroxiredoxin Chaperone Activity Is Critical for Protein Homeostasis in Zinc-deficient Yeast

Zinc is required for the folding and function of many proteins. In Saccharomyces cerevisiae, homeostatic and adaptive responses to zinc deficiency are regulated by the Zap1 transcription factor. One Zap1 target gene encodes the Tsa1 peroxiredoxin, a protein with both peroxidase and protein chaperone...

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Detalhes bibliográficos
Main Authors: MacDiarmid, Colin W., Taggart, Janet, Kerdsomboon, Kittikhun, Kubisiak, Michael, Panascharoen, Supawee, Schelble, Katherine, Eide, David J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3829442/
https://ncbi.nlm.nih.gov/pubmed/24022485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.512384
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