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Peroxiredoxin Chaperone Activity Is Critical for Protein Homeostasis in Zinc-deficient Yeast

Zinc is required for the folding and function of many proteins. In Saccharomyces cerevisiae, homeostatic and adaptive responses to zinc deficiency are regulated by the Zap1 transcription factor. One Zap1 target gene encodes the Tsa1 peroxiredoxin, a protein with both peroxidase and protein chaperone...

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Dettagli Bibliografici
Autori principali: MacDiarmid, Colin W., Taggart, Janet, Kerdsomboon, Kittikhun, Kubisiak, Michael, Panascharoen, Supawee, Schelble, Katherine, Eide, David J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3829442/
https://ncbi.nlm.nih.gov/pubmed/24022485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.512384
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