Bromodomain and Extra Terminal (BET) Inhibitor Suppresses Macrophage-Driven Steroid-Resistant Exacerbations of Airway Hyper-Responsiveness and Inflammation

BACKGROUND: Exacerbations of asthma are linked to significant decline in lung function and are often poorly controlled by corticosteroid treatment. Clinical investigations indicate that viral and bacterial infections play crucial roles in the onset of steroid-resistant inflammation and airways hyper...

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Detaylı Bibliyografya
Yayımlandı:PLoS One
Asıl Yazarlar: Nguyen, Thi Hiep, Maltby, Steven, Eyers, Fiona, Foster, Paul S., Yang, Ming
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2016
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5033241/
https://ncbi.nlm.nih.gov/pubmed/27657907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0163392
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