MMP-9 and MMP-2 Contribute to Neuronal Cell Death in iPSC Models of Frontotemporal Dementia with MAPT Mutations

How mutations in the microtubule-associated protein tau (MAPT) gene cause frontotemporal dementia (FTD) remains poorly understood. We generated and characterized multiple induced pluripotent stem cell (iPSC) lines from patients with MAPT IVS10+16 and tau-A152T mutations and a control subject. In cor...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Stem Cell Reports
Asıl Yazarlar: Biswas, Md Helal U., Almeida, Sandra, Lopez-Gonzalez, Rodrigo, Mao, Wenjie, Zhang, Zhijun, Karydas, Anna, Geschwind, Michael D., Biernat, Jacek, Mandelkow, Eva-Maria, Futai, Kensuke, Miller, Bruce L., Gao, Fen-Biao
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Elsevier 2016
Konular:
Report
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5032669/
https://ncbi.nlm.nih.gov/pubmed/27594586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2016.08.006
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller