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Differential regulation of FGFR3 by PTPN1 and PTPN2

Aberrant expression and activation of FGFR3 is associated with disease states including bone dysplasia and malignancies of bladder, cervix, and bone marrow. MS analysis of protein-phosphotyrosine in multiple myeloma cells revealed a prevalent phosphorylated motif, D/EYYR/K, derived from the kinase d...

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Detalhes bibliográficos
Publicado no:Proteomics
Main Authors: St-Germain, Jonathan R., Taylor, Paul, Zhang, Wen, Li, Zhihua, Ketela, Troy, Moffat, Jason, Neel, Benjamin G., Trudel, Suzanne, Moran, Michael F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5032629/
https://ncbi.nlm.nih.gov/pubmed/25311528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pmic.201400259
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