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Combining Yeast Display and Competitive FACS to Select Rare Hapten-Specific Clones from Recombinant Antibody Libraries

[Image: see text] The development of antibodies to low molecular weight haptens remains challenging due to both the low immunogenicity of many haptens and the cross-reactivity of the protein carriers used to generate the immune response. Recombinant antibodies and novel display technologies have gre...

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Publicat a:Anal Chem
Autors principals: Sun, Yue, Ban, Bhupal, Bradbury, Andrew, Ansari, G. A. Shakeel, Blake, Diane A.
Format: Artigo
Idioma:Inglês
Publicat: American Chemical Society 2016
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5032104/
https://ncbi.nlm.nih.gov/pubmed/27571429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.6b02334
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