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Cyclooxygenase-2 induced β1-integrin expression in NSCLC and promoted cell invasion via the EP1/MAPK/E2F-1/FoxC2 signal pathway

Cyclooxygenase-2 (COX-2) has been implicated in cell invasion in non-small-cell lung cancer (NSCLC). However, the mechanism is unclear. The present study investigated the effect of COX-2 on β1-integrin expression and cell invasion in NSCLC. COX-2 and β1-integrin were co-expressed in NSCLC tissues. C...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Pan, Jinshun, Yang, Qinyi, Shao, Jiaofang, Zhang, Li, Ma, Juan, Wang, Yipin, Jiang, Bing-Hua, Leng, Jing, Bai, Xiaoming
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5031967/
https://ncbi.nlm.nih.gov/pubmed/27654511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep33823
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