Energy crisis precedes global metabolic failure in a novel Caenorhabditis elegans Alzheimer Disease model

Alzheimer Disease (AD) is a progressive neurological disorder characterized by the deposition of amyloid beta (Aβ), predominantly the Aβ(1–42) form, in the brain. Mitochondrial dysfunction and impaired energy metabolism are important components of AD pathogenesis. However, the causal and temporal re...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Sci Rep
Autori principali: Fong, Sheng, Teo, Emelyne, Ng, Li Fang, Chen, Ce-Belle, Lakshmanan, Lakshmi Narayanan, Tsoi, Sau Yee, Moore, Philip Keith, Inoue, Takao, Halliwell, Barry, Gruber, Jan
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2016
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5031964/
https://ncbi.nlm.nih.gov/pubmed/27653553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep33781
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi