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Energy crisis precedes global metabolic failure in a novel Caenorhabditis elegans Alzheimer Disease model
Alzheimer Disease (AD) is a progressive neurological disorder characterized by the deposition of amyloid beta (Aβ), predominantly the Aβ(1–42) form, in the brain. Mitochondrial dysfunction and impaired energy metabolism are important components of AD pathogenesis. However, the causal and temporal re...
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| Publicat a: | Sci Rep |
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| Autors principals: | , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5031964/ https://ncbi.nlm.nih.gov/pubmed/27653553 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep33781 |
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