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Biology of proprotein convertase subtilisin kexin 9: beyond low-density lipoprotein cholesterol lowering
Proprotein convertase subtilisin kexin 9 (PCSK9) is a key regulator of low-density lipoprotein receptor levels and LDL-cholesterol levels. Loss-of-function mutations in PCSK9 gene are associated with hypocholesterolaemia and protection against cardiovascular disease, identifying PCSK9 inhibition as...
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| Veröffentlicht in: | Cardiovasc Res |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5031950/ https://ncbi.nlm.nih.gov/pubmed/27496869 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvw194 |
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