Clinical Genotyping of Non–Small Cell Lung Cancers Using Targeted Next-Generation Sequencing: Utility of Identifying Rare and Co-mutations in Oncogenic Driver Genes()

Detection of somatic mutations in non–small cell lung cancers (NSCLCs), especially adenocarcinomas, is important for directing patient care when targeted therapy is available. Here, we present our experience with genotyping NSCLC using the Ion Torrent Personal Genome Machine (PGM) and the AmpliSeq C...

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Vydáno v:Neoplasia
Hlavní autoři: Tafe, Laura J., Pierce, Kirsten J., Peterson, Jason D., de Abreu, Francine, Memoli, Vincent A., Black, Candice C., Pettus, Jason R., Marotti, Jonathan D., Gutmann, Edward J., Liu, Xiaoying, Shirai, Keisuke, Dragnev, Konstantin H., Amos, Christopher I., Tsongalis, Gregory J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Neoplasia Press 2016
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Original article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5031899/
https://ncbi.nlm.nih.gov/pubmed/27659017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neo.2016.07.010
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