The potential utility of re-mining results of somatic mutation testing: KRAS status in lung adenocarcinoma

KRAS mutant non-small cell lung cancers (NSCLCs) vary in clinical outcome depending on which specific KRAS mutation is present. Shorter progression free survival has been associated with KRAS variants G12C and G12V. Cell lines with these variants depend to a greater extent on the RAS/RAF/MEK/ERK sig...

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Bibliografiset tiedot
Julkaisussa:Cancer Genet
Päätekijät: Biernacka, Anna, Tsongalis, Peter D., Peterson, Jason D., de Abreu, Francine B., Black, Candice C., Gutmann, Edward J., Liu, Xiaoying, Tafe, Laura J., Amos, Christopher I., Tsongalis, Gregory J.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2016
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5506544/
https://ncbi.nlm.nih.gov/pubmed/27068338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cancergen.2016.03.001
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