Structural basis of synaptic vesicle assembly promoted by α-synuclein

α-synuclein (αS) is an intrinsically disordered protein whose fibrillar aggregates are the major constituents of Lewy bodies in Parkinson's disease. Although the specific function of αS is still unclear, a general consensus is forming that it has a key role in regulating the process of neurotra...

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Publicat a:Nat Commun
Autors principals: Fusco, Giuliana, Pape, Tillmann, Stephens, Amberley D., Mahou, Pierre, Costa, Ana Rita, Kaminski, Clemens F., Kaminski Schierle, Gabriele S., Vendruscolo, Michele, Veglia, Gianluigi, Dobson, Christopher M., De Simone, Alfonso
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2016
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5031799/
https://ncbi.nlm.nih.gov/pubmed/27640673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms12563
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