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Antidepressant-like activity of sildenafil following acute and subchronic treatment in the forced swim test in mice: effects of restraint stress and monoamine depletion

Sildenafil is a highly effective oral agent for the treatment of erectile dysfunction of multiple etiologies. Although in clinical practice sildenafil is often used in depressed patients, its influence on the pathophysiology of depression remains unclear. The aim of the present study was to evaluate...

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Vydáno v:Metab Brain Dis
Hlavní autoři: Socała, Katarzyna, Nieoczym, Dorota, Pieróg, Mateusz, Szuster-Ciesielska, Agnieszka, Wyska, Elżbieta, Wlaź, Piotr
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer US 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5031750/
https://ncbi.nlm.nih.gov/pubmed/27283174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11011-016-9852-8
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