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Antidepressant-like activity of sildenafil following acute and subchronic treatment in the forced swim test in mice: effects of restraint stress and monoamine depletion

Sildenafil is a highly effective oral agent for the treatment of erectile dysfunction of multiple etiologies. Although in clinical practice sildenafil is often used in depressed patients, its influence on the pathophysiology of depression remains unclear. The aim of the present study was to evaluate...

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Detalhes bibliográficos
Publicado no:Metab Brain Dis
Main Authors: Socała, Katarzyna, Nieoczym, Dorota, Pieróg, Mateusz, Szuster-Ciesielska, Agnieszka, Wyska, Elżbieta, Wlaź, Piotr
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5031750/
https://ncbi.nlm.nih.gov/pubmed/27283174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11011-016-9852-8
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