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Defective sumoylation pathway directs congenital heart disease

Congenital heart defects (CHDs) are the most common of all birth defects, yet molecular mechanism(s) underlying highly prevalent atrial septal defects (ASDs) and ventricular septal defects (VSDs) have remained elusive. We demonstrate the indispensability of “balanced” post-translational SUMO conjuga...

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Detalhes bibliográficos
Publicado no:Birth Defects Res A Clin Mol Teratol
Main Authors: Wang, Jun, Chen, Li, Wen, Shu, Zhu, Huiping, Yu, Wei, Moskowitz, Ivan P., Shaw, Gary M., Finnell, Richard H., Schwartz, Robert J
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5031480/
https://ncbi.nlm.nih.gov/pubmed/21563299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bdra.20816
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